Administer Activase® (alteplase) in patients with acute massive Pulmonary Embolism (PE) over a 2-hour infusion

Explore dosing and administration recommendations for pulmonary embolism

  • The recommended treatment dose is 100 mg administered by intravenous (IV) infusion over 2 hours.
  • Institute parenteral anticoagulation near the end of or immediately following the Activase infusion when the partial thromboplastin time or thrombin time returns to twice normal or less.

Access the Activase in Acute Massive Pulmonary Embolism Dosing Card >