Activase (t-PA) dosing and administration for acute ischemic stroke

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Identifying an Acute Ischemic Stroke
Rapid Response Protocols: Diagnostic Tools
Assessing Eligibility for Activase (t-PA) Therapy
Reconstitution, Dosing, and Administration
An Activase (t-PA) Success Story

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FAQ brochure

  • Helpful and concise in PDF format, this brochure provides answers to questions about Activase (t-PA)



FAQ brochure

Indication: Activase is indicated for the management of acute ischemic stroke in adults for improving neurological recovery and reducing the incidence of disability. Treatment should only be initiated within 3 hours after the onset of stroke symptoms, and after exclusion of intracranial hemorrhage by a cranial computerized tomography (CT) scan or other diagnostic imaging method sensitive for the presence of hemorrhage (see CONTRAINDICATIONS in the full prescribing information).

Safety Information: All thrombolytic agents increase the risk of bleeding, including intracranial bleeding, and should be used only in appropriate patients. Not all patients with acute ischemic stroke will be eligible for Activase therapy, including patients with evidence of recent or active bleeding; recent (within 3 months) intracranial or intraspinal surgery, serious head trauma, or previous stroke; uncontrolled high blood pressure; or impaired blood clotting.


Please see full prescribing information.


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